Merja Heinäniemi
Deputy Head of Unit
Professor
Institute of Biomedicine, School of Medicine, Faculty of Health Sciences
merja.heinaniemi@uef.fi | +358 40 355 3842
Research groups
Publications
24/70 items-
Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening
Gezelius, Henrik; Enblad, Anna Pia; Lundmark, Anders; Åberg, Martin; Blom, Kristin; Rudfeldt, Jakob; Raine, Amanda; Harila, Arja; Rendo, Verónica; Heinäniemi, Merja; Andersson, Claes; Nordlund, Jessica. 2024. NAR genomics and bioinformatics. 6: . lqae001 A1 Journal article (refereed), original research -
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells in Vitro
Selvarajan, Ilakya; Kiema, Miika; Huang, Ru Ting; Li, Jin; Zhu, Jiayu; Pölönen, Petri; Örd, Tiit; Õunap, Kadri; Godiwala, Mehvash; Golebiewski, Anna Kathryn; Ravindran, Aarthi; Mäklin, Kiira; Toropainen, Anu; Stolze, Lindsey K; Arce, Maximiliano; Magnusson, Peetra U; White, Stephen; Romanoski, Casey E; Heinäniemi, Merja; Laakkonen, Johanna P; Fang, Yun; Kaikkonen, Minna U. 2024. Arteriosclerosis, thrombosis, and vascular biology. 44: 1330-1345 A1 Journal article (refereed), original research -
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL
Gentile, Gaia; Poggio, Teresa; Catalano, Antonella; Voutilainen, Minna; Lahnalampi, Mari; Andrade-Martinez, Marta; Ma, Tobias; Sankowski, Roman; Goncharenko, Lina; Tholen, Stefan; Han, Kyuho; Morgens, David W.; Prinz, Marco; Lübbert, Michael; Engel, Sophia; Hartmann, Tanja Nicole; Cario, Gunnar; Schrappe, Martin; Lenk, Lennart; Stanulla, Martin; Duyster, Justus; Bronsert, Peter; Bassik, Michael C.; Cleary, Michael L.; Schilling, Oliver; Heinäniemi, Merja; Duque-Afonso, Jesús. 2024. Blood advances. 8: 2846-2860 A1 Journal article (refereed), original research -
ECCB2024: The 23rd European Conference on Computational Biology
Kukkonen-Macchi, Anu; Hautaniemi, Sampsa; Heil, Katharina F; Heinäniemi, Merja; Jensen, Lars Juhl; Junttila, Sini; Käll, Lukas; Laiho, Asta; Maccallum, Peter; Nykter, Matti; Persson, Bengt; Suomi, Tomi; Van Den Bossche, Tim; Nyrönen, Tommi H; Elo, Laura L. 2024. Bioinformatics. 40: ii1-ii3 B1 Non-refereed journal articles -
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia
Malyukova, Alena; Lahnalampi, Mari; Falqués-Costa, Ton; Pölönen, Petri; Sipola, Mikko; Mehtonen, Juha; Teppo, Susanna; Akopyan, Karen; Viiliainen, Johanna; Lohi, Olli; Hagström-Andersson, Anna K; Heinäniemi, Merja; Sangfelt, Olle. 2024. Genome biology. 25: . 143 A1 Journal article (refereed), original research -
A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies
Härkönen, Jouni; Pölönen, Petri; Deen, Ashik Jawahar; Selvarajan, Ilakya; Teppo, Hanna-Riikka; Dimova, Elitsa Y.; Kietzmann, Thomas; Ahtiainen, Maarit; Väyrynen, Juha P.; Väyrynen, Sara A.; Elomaa, Hanna; Tynkkynen, Niko; Eklund, Tiia; Kuopio, Teijo; Talvitie, Eva-Maria; Taimen, Pekka; Kallajoki, Markku; Kaikkonen, Minna U.; Heinäniemi, Merja; Levonen, Anna-Liisa. 2023. Redox biology. 61: A1 Journal article (refereed), original research -
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia
Kuusanmäki, Heikki; Dufva, Olli; Vähä-Koskela, Markus; Leppä, Aino-Maija; Huuhtanen, Jani; Vänttinen, Ida Maria; Nygren, Petra Johanna; Klievink, Jay; Bouhlal, Jonas Otto Vilhelm; Pölönen, Petri; Zhang, Qi; Adnan Awad, Shady; Mancebo-Pérez, Cristina; Saad, Joseph; Miettinen, Juho J.; Javarappa, Komal Kumar; Aakko, Sofia; Ruokoranta, Tanja; Eldfors, Samuli; Heinäniemi, Merja; Theilgaard-Mönch, Kim; Wartiovaara-Kautto, Ulla; Keränen, Mikko A I; Porkka, Kimmo; Konopleva, Marina; Wennerberg, Krister. 2023. Blood. 141: 1610-1625 A1 Journal article (refereed), original research -
Generation of a Zebrafish Knock-In Model Recapitulating Childhood ETV6::RUNX1-Positive B-Cell Precursor Acute Lymphoblastic Leukemia
Zapilko, Veronika; Moisio, Sanni; Parikka, Mataleena; Heinäniemi, Merja; Lohi, Olli. 2023. Cancers. 15: A1 Journal article (refereed), original research -
Genomic Determinants of Therapy Response in ETV6::RUNX1 Leukemia
Oksa, Laura; Moisio, Sanni; Maqbool, Khurram; Foroughi-Asl, Hassan; Kramer, Roger; Nikkilä, Atte; Vepsäläinen, Kaisa; Duque-Afonso, Jesus; Hauer, Julia; Nordlund, Jessica; Wirta, Valtteri; Lohi, Olli; Heinäniemi, Merja. 2023. Blood abstract -
In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
Fischer, Anja; Lersch, Robert; de Andrade Krätzig, Niklas; Strong, Alexander; Friedrich, Mathias J.; Weber, Julia; Engleitner, Thomas; Öllinger, Rupert; Yen, Hsi-Yu; Kohlhofer, Ursula; Gonzalez-Menendez, Irene; Sailer, David; Kogan, Liz; Lahnalampi, Mari; Laukkanen, Saara; Kaltenbacher, Thorsten; Klement, Christine; Rezaei, Majdaddin; Ammon, Tim; Montero, Juan J.; Schneider, Günter; Mayerle, Julia; Heikenwälder, Mathias; Schmidt-Supprian, Marc; Quintanilla-Martinez, Leticia; Steiger, Katja; Liu,. 2023. Cell genomics. 3: A1 Journal article (refereed), original research